The airport said it is clearing the airfield and operations will resume “at the earliest opportunity”.
The airport added in a tweet that passengers’ health and safety will “always be our top priority,” and advised them to contact their airline for the most up-to-date flight information.
Temperatures in parts of the UK fell below -10C (14F) overnight.
Following a drop in temperatures, a number of severe weather warnings for snow and ice have been issued across the UK in recent days.
According to flight tracking website FlightRadar24, a Virgin Atlantic flight from Atlanta was diverted from Manchester to London due to runway closures.
One passenger at Manchester Airport stated that they had already experienced two hours of delays and were now seated on a plane that was “going nowhere” for another hour.
Drumnadrochit in the Highlands near Inverness reached -10.4C (13.28F) in the early hours of Thursday, the coldest recorded temperature of the year thus far.
Manchester Airport was forced to close both runways after the temperature in Topcliffe, north Yorkshire, dropped to -7.4C (18.68F), the coldest in England.
The Met Office has issued a yellow weather warning for snow and ice in Manchester and other parts of the UK until midday today, predicting “further disruption” from wintry showers.
Forecasters expect milder air to arrive in Northern Ireland and Scotland on Friday afternoon.
Drivers have been urged to exercise caution following a crash involving a double-decker bus and a motorcycle in freezing conditions in Somerset on Tuesday.
In just five hours on Monday night, Avon and Somerset Police received over 100 reports of road-related incidents, the majority of which were caused by icy conditions.
Between 6 p.m. and 11 p.m., the police received 53 reports of collisions, seven of which resulted in injuries.
The UK Health Security Agency has issued a level three cold weather alert, warning of conditions that “could increase the health risks to vulnerable patients and disrupt the delivery of services” until 9 a.m. on Friday.
