The teenagers, both 17, were arrested in the Ashford area of Kent on Friday 10 May on suspicion of attempted murder and possession of a firearm with intent to endanger life.
They were transferred to London for questioning and were later charged with attempted murder and possession of a firearm with intent to endanger life.
Both were remanded in custody to appear in court on Monday, 13 May.
Police were called to Whalebone Lane South in Dagenham at about 5.20pm on Thursday, 2 May following reports that a man has been stabbed.
Shortly after, a second call was received from a member of the public reporting gunshots heard in the area.
Officers and London Ambulance Service attended and found a 19-year-old man, with what appeared to be stab injuries. He was taken to hospital where it was confirmed that he had been stabbed and also shot.
He remains in hospital in a critical condition. His next of kin has been informed.
Five men and a woman, aged between 18 and 25 years old, had previously been arrested on suspicion of attempted murder. They have since been bailed pending further enquiries.
Detectives from the Met’s Specialist Crime Command (Trident) investigate.
Anyone with information or footage relating to this incident should call 101 quoting 5857/02May.
To remain 100 per cent anonymous, call Crimestoppers on 0800 555 111 or visit crimestoppers-uk.org.
